Start: September 12, 2024 3:30 p.m.
End: September 12, 2024 4:30 p.m.
New Avenue for Single Electron Chemistry of Aromatic N-oxides in Synthesis and Catalysis
Dr. Yongming Deng
Assistant Professor
Department of Chemistry
Indiana University - Indianapolis
Thursday, 09/12 @ 3:30 PM
FB 253
The Deng group focuses on the investigations of unconventional single-electron transfer process of aromatic N-oxides to develop novel and practical synthetic methods and hydrogen-atom transfer catalysis. Our group recently developed a novel photocatalytic strategy for the generation of reactive and controllable β-oxypyridinium radical through mild visible-light photoredox catalyzed single-electron oxidation of an alkyne/pyridine N-oxide system. By applying this strategy, we have developed various vinyl radical cascade reactions for the facile synthesis of heterocyclic and polycyclic compounds. Furthermore, our group recently disclosed that, in conjunction with an acridinium photoredox catalyst, readily available and tunable pyridine N-oxides could serve as effective hydrogen atom transfer (HAT) catalysts for site-selective C-H functionalization of a broad range of substrates, including unactivated alkanes.