Najma Javed

Najma Javed

Professor of Physiology


Room:CL 359F


Ph.D.-Physiology, Ohio State University, 1992
M.S.-Physiology, Ball State University, 1987
M.D.-Medicine & Surgery, F.J. Medical College; Lahore, Pakistan, 1975

Research Interests

Najma Javed specializes in the interaction of neural, immune, and endocrine mechanisms in human gastrointestinal disorders.

Read more about Dr. Javed's research.


Whitacre C. C., N. H. Javed, I. E. Gienapp, and K. L. Cox. “Oral Tolerance as a Therapeutic Approach to Autoimmune Disease: Administration of Peptide Antigens.” In: Peptides: Chemistry, Structure and Biology, Ed. P. T. Kaumaya and R. Hodges. England: Mayflower Sci. Ltd. P 764, 1996.

Helen J. Cooke, Najma Javed and Fievus Christofi. (2003) “Enteric Neural Reflexes and Secretion.” In: Autonomic Neuroimmunology, Vol 16, pp. 35-59. Edited by: John Bienenstock, Edward J. Goetzl , and Michael G. Blennerhasset. Series Editor: Geoffrey Burnstock. Taylor & Francis, New York and London.

Javed, N.H., Furman, D., & Khubchandani, J. (2013). The regulatory effects of Bifidobacterium Infantis on the secretomotor activity of the enteric nervous system. Chronicles of Young Scientists, 4(2), 114-120.

Xue J, Askwith C, Javed NH, Cooke HJ. Autonomic nervous system and secretion across the intestinal mucosal surface. Auton Neurosci. 2007 Apr 30;133(1):55-63. Epub 2007 Mar 2.

Guzman, J,., Yu JG, Z Suntres , A. Bosarov, H Cooke , N Javed, H Palatini , HH Hassanain, AJ Cardounel , A Javed , I Grants, JE Wunderlioch, FL Christofi. ADO3R as a therapeutic target in experimental colitis: Proof by validated high-density oligonucleotide microarray analysis. Inflammatory Bowel Disease 12:766-789, 2006.

Wunderlich, JE, J Xue, M Kim, NH Javed, F.L. Christofi, Z Suntres, JG Yu, I Grants, HJ Cooke. Mechanical stimulation of human enterochromaffin-BON cells release adenosine to act at A3 receptors to modulate 5-HT release. Gastroenterology, p.A-160, 2004.

Fievos L. Christofi, Minsoo Kim, Jacqueline E. Wunderlich, Jianjing Xue, Zach Suntres, Arturo Cardounel, Najma H. Javed, Jun Ge Yu, Iveta Grants, and Helen J. Cooke. Endogenous Adenosine Differentially Modulates 5-Hydroxytryptamine Release from a Human Enterochromaffin Cell Model (BON). Gastroenterology, 127: 188-202, 2004.

Helen J. Cooke, Jianjing Xue, Jun Ge Yu, Jacqueline Wunderlich, Y.-Z. Wang, Jorge Guzman, Najma Javed, Fievos L. Christofi. Mechanical Stimulation Releases Nucleotides that Activate P2Y1 Receptors to Trigger Neural Reflex Chloride Secretion in Guinea Pig Distal Colon. Journal of Comparative Neurology, 469: 1-15, 2004.

Fievos L. Christofi, Jacqueline Wunderlich, Jung Ge Yu, Y-Z. Wang, Jianjing Xue, Jorge Guzman, Najma Javed, Helen Cooke. Mechanically-Evoked Reflex Electrogenic Chloride Secretion in Rat Distal Colon is Triggered by Endogenous Nucleotides Acting at P2Y1, P2Y2 and P2Y4 Receptors. Journal of Comparative Neurology, 469: 16-36, 2004.

Kim M., N. H. Javed, J. Yu, F. Christofi, and H. J. Cooke. ¡§Mechanical Stimulation Activates GƒÑq Signaling Pathways and 5-Hydroxytryptamine Release from Human Carcinoid BON Cells. Journal of Clinical Investigation 108 (7): 1051-1059, 2001.

Kim M., H. J. Cooke, N. H. Javed, H. V. Carey, F. Christofi and H. E. Raybould. D-Glucose Releases 5-Hydroxytryptamine from Human BON Cells as a Model of Enterochromaffin Cells. Gastroenterology, 121 (6): 1400-1406, 2001.

Meyer, A. L., J. Benson, F. Song, N. Javed, I. Gienapp, J. Goverman, T. A. Brabb, L. Hood, and C. C. Whitacre. Rapid Depletion of Peripheral Antigen-Specific T Cells in TCR Transgenic Mice Following Oral Administration of Myelin Basic Protein. Journal of Immunology 166: 5773-5782, 2001.

Kotecki, J. E., D. E. Siegel, and N. H. Javed. Outsourcing Your Web Presence: Questions and Considerations for the Health Professional. Journal of Health Education, Volume 29 (3):195-197, 1998.

Professional Organizations:

American Physiological Society
American Association of Immunologists
Sigma Xi Scientific Research Society
Indiana Academy of Science
Eta Sigma Gamma National Health Education Honorary
Pakistan Medical Council
The National Multiple Sclerosis Society
American Association of University Women
Association of Faculty and Professional Women, Ohio State University

Course Schedule
Course No. Section Times Days Location
Human Physiology 215 1 1000 - 1250 W FB, room 457
Human Physiology 215 1 1600 - 1750 M W FB, room 101
Human Physiology 215 2 0800 - 1050 R FB, room 457
Human Physiology 215 2 1600 - 1750 M W FB, room 101
Human Physiology 215 3 1100 - 1350 T FB, room 457
Human Physiology 215 3 1600 - 1750 M W FB, room 101
Human Physiology 215 4 1400 - 1650 R FB, room 457
Human Physiology 215 4 1600 - 1750 M W FB, room 101
Cardiovascular Physi 614 1 1200 - 1250 M W F FB, room 103