Over 100 studies of physiological indicators of stress use college students as research subjects. Only three of these studies, however, examine life-style factors specific to college students. This research aims to fill this gap by focusing on the influence of college life-style variables on blood pressure and stress-related symptoms. Our preliminary analyses demonstrate that systolic blood pressure (SBP) is associated with alcohol consumption, smoking, number of roommates, family composition, and students’ satisfaction with their housing situation. Stress-related symptoms were associated with patterns of alcohol use, relations with roommates, financial situation, parental control of financial resources, subject perception of their response to stress, and a scale of stressors specific to college life.