Scott Trappe, Ph.D. John and Janice Fisher Professor of Exercise Science Director, Human Performance Laboratory

Education:

B.S.  University of Northern Iowa; 1989; Major: Science; Minor: Chemistry
M.S.  University of Colorado; 1991; Major - Exercise Science
Ph.D.  Ball State University; 1994; Major - Human Bioenergetics
Post-Doc Ball State University/Marquette University - Muscle Physiology;       1994-1997

Research Interests:

Human skeletal muscle contractile function and structure with a focus on cellular physiology and biology.  Main areas of emphasis: 1) adaptation of skeletal muscle to a reduction in physical activity and exercise countermeasures during periods of disuse (aging and spaceflight), and 2) skeletal muscle adaptation to periods of overtraining and taper (reduced training/rest) as it relates to sports performance.

Current Projects:

Single Muscle Fiber Contractile Properties With Aging

Principal Investigator: Scott Trappe
Agency: National Institutes of Health (NIH)
Type: R01-AG18409 Period: 9/01/01-8/31/06

The major goals of this research are to examine the single muscle fiber contractile properties before and after resistance training in young and old men and women.

Effect of Prolonged Space Flight on Human Skeletal Muscle

Principal Investigator: Robert Fitts, Co-Investigator: S. Trappe
Agency: National Aeronautics and Space Administration  
Period: 1/01/01-12/31/06

The major goals of this research are to examine the whole muscle and single muscle fiber contractile properties on astronauts before and after a 4-6 month stay aboard the International Space Station (ISS).

Analgesics and Resistance Training in Older Individuals

Principal Investigator: T. A. Trappe, Co-Investigator: S. Trappe
Agency: National Institute of Aging
Type: R01 AG20532 Period: 3/01/04-2/28/09

The major goals of this research are to examine the interactive effects of common over-the-counter analgesics on skeletal muscle protein synthesis and the hypertrophic response to resistance training in older women and men.

Influence of Exercise on Human Single Muscle Fiber Function with Long-Term Bedrest

Principal Investigator: S Trappe, Co-investigator: T. Trappe
Agency:  National Aeronautical and Space Administration
Period: 4/01/04-8/31/06

The major goals of this research are to examine the influence resistance training on single muscle fiber function and skeletal muscle myosin and actin content during 60 days of simulated spaceflight and countermeasures in women. This project is being completed at the MEDES bedrest facility in Toulouse, France.

Recent Publications:

Trappe, S., T. Trappe, P. Gallagher, M. Harber, B. Alkner, P. Tesch. Human Single Muscle Fiber Function with 84-d Bedrest and Resistance Exercise.  J. Phys. 557.2: 501-513, 2004.

Jemiolo, B. and S. Trappe.  Single Muscle Fiber Gene Expression in Human Skeletal Muscle: Validation of Internal Control with Exercise.  Biochem. Biophys. Res. Comm.  320: 1043-1050, 2004

Harber, M, P. Gallagher, A. Creer, K. Minchev and S. Trappe.  Single muscle fiber contractile properties during a competitive season in male runners. Am. J. Physiol.  R1124-R1131, 2004.

Raue, U., B. Terpstra, D. Williamson, P. Gallagher and S. Trappe.  Effects of short-term concentric vs. eccentric resistance training on single muscle fiber MHC distribution in humans.  Int. J. Sports Med. 26: 339-343, 2005.

Carroll, C, P. Gallagher, M. Seidle and S. Trappe.  Skeletal muscle characteristics of individuals with multiple sclerosis.  Arch. Phys. Med. Rehabil. 86: 224-229, 2005.

Yang, Y, A. Creer, B. Jemiolo and S. Trappe.  Time course of myogenic and metabolic gene expression in response to acute exercise in human skeletal muscle.  J. Appl. Physiol.  98: 1745-1752, 2005.

Creer, A., P. Gallagher, D. Slivka, B. Jemiolo, W. Fink and S. Trappe.  Influence of muscle glycogen availability on Erk1/2 and Akt signaling after resistance exercise in human skeletal muscle.  J. Appl. Physiol.  99: 950-956, 2005

Gallagher, P, S. Trappe, A. Creer, M. Harber, S. Mazzetti, T. Trappe, B. Alkner and P. Tesch.  Effects of 84-days of bedrest and resistance training on single muscle fibre myosin heavy chain distribution in human vastus lateralis and soleus muscles.  Acta Physiol. Scand.  185: 61-69, 2005.

Trappe, T., S. Trappe, G. Lee, J. Widrick, R. Fitts and D. Costill.  Cardiorespiratory responses to physical work during and following 17 days of bedrest and spaceflight. J. Appl. Physiol.  In Press.